LANTUSTITR: Insulin Glargine in Type 2 Diabetes Mellitus

The Determination of the First Dose and the Optimal Time of Administration of Insulin Glargine Combined With Oral Antidiabetic Drug in Poorly Controlled Type II Diabetic Patients

The rationale of the study is to determine:

• the first dose and the titration of basal insulin
• the exact daily time administration of basal insulin in poorly controlled type II diabetic patients.

Inclusion Criteria:

• Type 2 Diabetes Mellitus
• Insufficient combined oral antidiabetic treatment (biguanide + sulfonylurea)
• BMI >25 kg/m2 , <30 kg/m2
• HbA1c value >7.0%, <9.0% within one month

Exclusion Criteria:

• Type 1 Diabetes Mellitus
• Known malignancy
• Drug or alcohol abuse
• Severe liver disease
• Renal failure (se Creatinine > 150 micro mol/l)

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.