Topiramate for the Treatment of Methamphetamine Dependence - 1

Phase 2, Double-Blind, Placebo-Controlled Trial of Topiramate for the Treatment of Methamphetamine Dependence

The purpose of this study is to assess the efficacy and safety of topiramate as compared to placebo in reducing methamphetamine use in subjects with methamphetamine dependence.

Inclusion Criteria:

• Treatment seeking individuals as the time of the study
• Must be able to proved written informed consent
• Must have a body mass index greater than 18 kg/m(2)
• Must meet DSM-IV criteria for methamphetamine dependence
• Must currently be using methamphetamine as confirmed by a positive urine test over the past 14 days
• If female of child bearing potential, must agree to use birth control

Exclusion Criteria:

• Please contact the site for more information