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| ID | Type | Description | Link |
|---|---|---|---|
| 229/03 |
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| Name | Class |
|---|---|
| Action on Addiction | OTHER |
Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press). As these interventions target personality traits linked to risk for addictive and non-addictive mental disorders, the aim of this study is to examine the extent to which this approach can prevent and/or reduce alcohol and drug misuse as well as have an impact on the onset or severity of emotional and behavioural problems in young people.
Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press). As these interventions target personality traits linked to risk for addictive and non-addictive psychopathology, the aim of this study is to examine the extent to which this approach is effective in preventing and/or reduce alcohol and drug misuse and concurrent psychiatric symptoms in young people.
Method: 875 Participants aged 13-16 years will be screened for personality risk in school-wide self-report assessments. Participants will be randomly assigned to a personality matched cognitive-behavioural intervention or a no-intervention control. The personality matched interventions will target four personality risk factors: negative thinking (NT), anxiety sensitivity (AS), impulsivity (IMP) and sensation seeking (SS). Outcome evaluation will occur 6, 12, 18 and 24 months post intervention. Primary outcomes will be time to onset and severity of alcohol and illicit substance use and misuse. Secondary outcome variables will include depressive symptoms, panic attack rates, reckless and antisocial behaviour. Secondary analyses involving genetic, cognitive and coping skills measures will examine moderators of treatment effects.
Hypotheses: It is expected that personality-targeted interventions will have personality-specific effects on aspects of addictive and non-addictive psychopathology to which each personality risk group is most susceptible.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| learning to cope with your impulsivity | Experimental | cognitive behavioural intervention teaching high impulsive youth how to manage their impulsive thinking and behaviours |
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| learning to cope with your sensation seeking | Experimental | cognitive-behavioural intervention teaching high sensation seeking youth how to manage their need for stimulation and excitement |
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| learning to cope with your anxiety sensitivity | Experimental | cognitive behavioural intervention targeting catastrophic thinking in high anxiety sensitive youth |
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| learning to manage your negative thinking | Experimental | cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PRE-Venture: Personality Risk Education | Behavioral | Motivational and Cognitive-Behavioural interventions targeting four personality risk factors for substance misuse. Two, 90-minute group sessions conducted at school with personality-matched peers and trained psychologists/councellors and co-facilitators. |
| Measure | Description | Time Frame |
|---|---|---|
| Time to onset and severity of drug use | time to illicit drug use events, assessed using the Reckless Behaviour Questionnaire | 2 years |
| Frequency and Quantity of Drinking | 2 years | |
| Problem drinking symptoms | Assessed using an abbreviated version of the Rutger's Alcohol Problem Index | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking | Assessed using the Brief Symptom Inventory, the Reckless Behaviour Questionnaire, and the Drinking Motives Questionnaire. | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Patricia J. Conrod, Ph.D. | Institute of Psychiatry | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Psychiatry, King's College London | London | SE5 8AF | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15714051 | Background | Stewart SH, Conrod PJ, Marlatt GA, Comeau MN, Thush C, Krank M. New developments in prevention and early intervention for alcohol abuse in youths. Alcohol Clin Exp Res. 2005 Feb;29(2):278-86. doi: 10.1097/01.alc.0000153547.34399.e8. | |
| 10998950 | Background | Conrod PJ, Pihl RO, Stewart SH, Dongier M. Validation of a system of classifying female substance abusers on the basis of personality and motivational risk factors for substance abuse. Psychol Addict Behav. 2000 Sep;14(3):243-56. doi: 10.1037//0893-164x.14.3.243. |
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| ID | Term |
|---|---|
| D000437 | Alcoholism |
| D019966 | Substance-Related Disorders |
| D003863 | Depression |
| D016584 | Panic Disorder |
| D019955 | Conduct Disorder |
| D016739 | Behavior, Addictive |
| D063425 | Binge Drinking |
| D001008 | Anxiety Disorders |
| D000987 | Antisocial Personality Disorder |
| ID | Term |
|---|---|
| D019973 | Alcohol-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
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| 10998949 | Background | Conrod PJ, Stewart SH, Pihl RO, Cote S, Fontaine V, Dongier M. Efficacy of brief coping skills interventions that match different personality profiles of female substance abusers. Psychol Addict Behav. 2000 Sep;14(3):231-42. doi: 10.1037//0893-164x.14.3.231. |
| 11768546 | Background | Comeau N, Stewart SH, Loba P. The relations of trait anxiety, anxiety sensitivity, and sensation seeking to adolescents' motivations for alcohol, cigarette, and marijuana use. Addict Behav. 2001 Nov-Dec;26(6):803-25. doi: 10.1016/s0306-4603(01)00238-6. |
| 30865304 | Derived | Edalati H, Afzali MH, Castellanos-Ryan N, Conrod PJ. The Effect of Contextual Risk Factors on the Effectiveness of Brief Personality-Targeted Interventions for Adolescent Alcohol Use and Misuse: A Cluster-Randomized Trial. Alcohol Clin Exp Res. 2019 May;43(5):997-1006. doi: 10.1111/acer.14016. Epub 2019 Apr 8. |
| 20869813 | Derived | Topper LR, Castellanos-Ryan N, Mackie C, Conrod PJ. Adolescent bullying victimisation and alcohol-related problem behaviour mediated by coping drinking motives over a 12 month period. Addict Behav. 2011 Jan-Feb;36(1-2):6-13. doi: 10.1016/j.addbeh.2010.08.016. Epub 2010 Sep 24. |
| 20732631 | Derived | O'Leary-Barrett M, Mackie CJ, Castellanos-Ryan N, Al-Khudhairy N, Conrod PJ. Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers. J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):954-963.e1. doi: 10.1016/j.jaac.2010.04.011. Epub 2010 Jul 31. |
| 20048226 | Derived | Conrod PJ, Castellanos-Ryan N, Strang J. Brief, personality-targeted coping skills interventions and survival as a non-drug user over a 2-year period during adolescence. Arch Gen Psychiatry. 2010 Jan;67(1):85-93. doi: 10.1001/archgenpsychiatry.2009.173. |
| D001519 | Behavior |
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D003192 | Compulsive Behavior |
| D007175 | Impulsive Behavior |
| D000428 | Alcohol Drinking |
| D004327 | Drinking Behavior |
| D010554 | Personality Disorders |