IMRT (upper third of vagina & para-vaginal tissue and the common, external and internal iliac nodal regions) 160-180 cGy daily fractions for a total dose of 4500-5120 cGy. Once a day treatment four to five days a week for approximately 6 weeks.

Intracavitary vaginal brachytherapy - some patients will be given this and it will be decided by the treating physician.

Carboplatin - AUC 6, IV over 30-60 minutes following completion of paclitaxel, given once every 3 weeks (3 weeks=1 cycles) for a total of 6 cycles

Paclitaxel - 175 mg/m2, 3 hour continuous IV infusion, administered prior to carboplatin, given once every 3 weeks (3 weeks=1 cycles) for a total of 6 cycles

The study will be deemed infeasible if greater than 10% of patients experience one of the following:

• Patient cannot be given the treatment because her anatomy is such that a dosimetrically satisfactory treatment plan cannot be devised for her.
• The patient experiences any grade 4 acute toxicity judged to be related to her external radiation treatment.
• Within 1 year of the start of radiation therapy, the patient develops any grade 4 late toxicity judged to be related to her external radiation treatment.
• Within 1 year of the start of radiation therapy, the patient develops any in-field pelvic recurrence.
• Within 1 year of the start of radiation therapy, the patient dies from causes judged to be related to her treatment.