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| Name | Class |
|---|---|
| Swedish Cancer Foundation | OTHER |
| Medical Research Council | OTHER_GOV |
The study is designed to evaluate whether daily insulin treatment to weight losing cancer patients attenuates progression of cancer cachexia and improves metabolism.
Randomized study with long-term follow-up based on survival, health related quality of life, food intake, resting energy expenditure, body composition, exercise capacity and measurement of metabolic efficiency.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Insulatard, flexpen | Drug |
| Measure | Description | Time Frame |
|---|---|---|
| Health related quality of life, | ||
| food intake, | ||
| resting energy expenditure, | ||
| body composition, | ||
| metabolic efficiency, | ||
| spontaneous physical activity, | ||
| blood and hormonal tests | ||
| serum tumor markers |
| Measure | Description | Time Frame |
|---|---|---|
| Survival |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kent G Lundholm, MD | Department of Surgery, Göteborg University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Surgery, Inst of Clinical Sciences | Gothenburg | SE413 45 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22727547 | Derived | Wallengren O, Bosaeus I, Lundholm K. Dietary energy density, inflammation and energy balance in palliative care cancer patients. Clin Nutr. 2013 Feb;32(1):88-92. doi: 10.1016/j.clnu.2012.05.023. Epub 2012 Jun 23. |
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| ID | Term |
|---|---|
| D000068880 | Isophane Insulin, Human |
| ID | Term |
|---|---|
| D007336 | Insulin, Isophane |
| D049528 | Insulin, Long-Acting |
| D061385 | Insulins |
| D010187 | Pancreatic Hormones |
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| D036361 |
| Peptide Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D061386 | Insulin, Regular, Human |
| D007328 | Insulin |
| D011384 | Proinsulin |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |