Quetiapine for Primary Insomnia Patients : A Randomized Controlled Trial

Quetiapine for Primary Insomnia Patients : A Randomized Controlled Trial

Primary insomnia patients will sleep with Quetiapine not better than without Quetiapine

1. Primary insomnia will be diagnosed according to DSM-IV-TR
2. After consenting, cases will be divided (double blind randomization)in to two arms 2.1 sleep hygiene with placebo group 2.2 sleep hygiene with Quetiapine group
3. outcome measurement: sleep diary, sleep satisfaction visual analog scale and sleep satisfaction likert scale
4. statistical method: dependent T test

Inclusion Criteria:

• Primary insomnia Patients by DSM-IV-TR criteria
• cases enrolled: age 18-65 educated

Exclusion Criteria:

• Currently receiving Quetiapine or other hypnotic drugs
• Liver disease
• Patients with heart Dz, Hypertension, thyroid disease
• History of epilepsy or febrile convulsion
• pregnant
• cognitive impairments
• History of Orthostatic Hypotension
• Patient with other Psychiatric conditions or Drug dependence