Arthralgia During Anastrozole Therapy for Breast Cancer

A Multicentre, Open Study Assessing Joint Disorders Under ARIMIDEX® (1mg/Day) as Adjuvant Treatment in Post Menopausal Women With Early Breast Cancer

The purpose of this study is to describe the joint symptoms and structural joint changes under anastrozole as adjuvant treatment in postmenopausal women with early breast cancer.

Inclusion Criteria:

• Post menopausal woman with a breast cancer and scheduled for an adjuvant treatment with anastrozole
• WHO performance status 0, 1 or 2
• Provision of written informed consent

Exclusion Criteria:

• Recurrence of breast cancer, inflammatory rheumatism
• treatment by chondromodulator, oral glucocorticoid, aromatase inhibitor, anti estrogen, Herceptin
• Diabetes treated by insulin
• Severe renal or hepatic disease
• Known hypersensitivity to anastrozole