The Genetic Basis for Familial Cardiomyopathy in Patients... | NCT00322582

Studies
The Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic Cardiomyopathy

NCT00322582

Sponsor

Carmel Medical Center

Status

Terminated

Last Update Posted

Jan 25, 2012Estimated

Enrollment

41Actual

Phase

Not provided

Conditions

Cardiomyopathy

Interventions

Not provided

Countries

Israel

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

ID	Type	Description	Link
136-2005

Status Module

Record Verification Date

Jan 2007

Overall Recruitment Status or Expanded Access Status

Terminated

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

no financial resources were available to complete the study

Expanded Access Info

Start Date

May 2007

Primary Completion Date

Feb 2009Actual

Completion Date

Feb 2009Actual

First Submitted Date

May 5, 2006

First Submission Date that Met QC Criteria

May 5, 2006

First Posted Date

May 8, 2006Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 24, 2012

Last Update Posted Date

Jan 25, 2012Estimated

Description Module

Brief Summary

In many of the patients with cardiomyopathy, the etiology is not clear . In about 30% there is a family history of cardiomyopathy .Our aim is to study the genetics basis for these patients with cardiomyopathy with no clear etiology and who have a first degree family relative with cardiomyopathy as well.

Detailed Description

A total of 950 blood samples will be collected from patients with idiopathic cardiomyopathy and their relatives and will be analysed for genetics analysis.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

41Actual

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

history of cardiomyopathy
etiology not known
family history of cardiomyopathy
ability to understand and sign the informed consent

Exclusion Criteria:

refusal to participate
pregnancy
current participation in another active treatment study

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

90 Years

Standard Ages

AdultOlder Adult

Study Population

History of cardiomyopathy

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Offer Amir, MD	Lady Davis Carmel Hospital	Study Director

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Carmel Medical Center		Haifa		34362	Israel

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
16018289	Background	Murphy RT, Starling RC. Genetics and cardiomyopathy: where are we now? Cleve Clin J Med. 2005 Jun;72(6):465-6, 469-70, 472-3 passim. doi: 10.3949/ccjm.72.6.465.

ID	Term
D006331	Heart Diseases
D002318	Cardiovascular Diseases