Monocentric, cleansing evaluation pilot study in patients undergoing colonoscopy.

Open prospective pilot monocentric phase II clinical trial evaluating the therapeutic efficacy of a new "Low Dose Bowel Prep" formulation for gut cleansing prior to colonoscopy.

Thirty patients admitted to the hospital (inpatients) planned to undergo a complete colonoscopy will have gut cleansing with the "Low Dose Bowel Prep" using a one-step intake mode.

Inclusion Criteria:

• male or female, inpatients 18 to 65 years old with indication for complete colonoscopy
• the patient's written informed consent must be obtained prior to inclusion
• willing and able to complete the entire procedure and to comply with study instructions

Exclusion Criteria:

• ileus or toxic megacolon
• intestinal obstruction or perforation
• known of G6PD insufficiency
• history of any colonic surgery
• ischaemic cardiovascular disease
• untreated or uncontrolled arterial hypertension (max >170mmHg, min >100mmHg)
• renal insufficiency (creating above 45µmol/l)
• abnormal laboratory values (clinically significant) for sodium, potassium,chloride, creatinine and hematocrit
• cirrhosis of liver (Child-Pugh grade B or C)
• females who are pregnant, nursing or planning a pregnancy. Females of child bearing potential not using reliable methods of contraception.
• concurrent participation in an investigational drug study or participation within 30 days of study entry
• subject has a condition or is in a situation which in the investigators opinion may put the subject at significant risk, may confound the study results or may interfere significantly