The Effect Of AVANDIA On The Late Asthmatic Response

A Randomised Double-blind Two-period Crossover Study to Investigate the Effect of Treatment With Repeat Doses of a PPAR Gamma Agonist on the Allergen-induced Late Asthmatic Response in Subjects With Mild Asthma Compared With Repeat Doses of Placebo

This study is to investigate the effects of AVANDIA on the asthmatic response.

Inclusion criteria:

• Mild asthmatic treated with short-acting beta agonists only, non-smoker.

Exclusion criteria:

• Inability to abstain from medications other than short-acting beta agonists and paracetamol.
• Recent administration of steroids.
• Recent respiratory infection or exacerbation of asthma.