Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Abnormal Labor

Placebo-Controlled Randomized Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Dysfunctional Labor

The purpose of this study is to determine whether propranolol is better than oxytocin for the treatment of labor abnormalities. The endpoint is the rate of vaginal delivery experienced by women receiving prolonged oxytocin versus propranolol.

This trial was designed to test if propranolo can reduce the c section rate for dysfuctional labor. Due to stringent inclution and exclusion criteria and low enrollment the study was closed.

Inclusion Criteria:

• Must be term pregnancy (> 37 weeks)
• Vertex presentation
• Active labor (4-5 centimeters dilated)

Exclusion Criteria:

• Heart disease
• Diabetes
• Currently taking propranolol
• Contraindications to labor or vaginal delivery
• Multiple gestations
• Preterm
• Chorioamnionitis