SPP100 Dose Finding Study in Japan

Dose-finding Study of SPP100 in Essential Hypertension

This study will evaluate the efficacy of SPP100 in lowering blood pressure in patients with essential hypertension.

Inclusion Criteria:

1. Mild to moderate essential hypertension
2. Age: ≥20 years old and <80 years old (at time informed consent obtained)
3. Sex: N/A
4. Admission status: Outpatient

Exclusion Criteria:

1. Pregnant women, lactating women, potentially pregnant women, or women who wish to become pregnant
2. Patients having a mean sitting diastolic blood pressure of ≥110 mmHg and/or a mean sitting systolic blood pressure of ≥180 mmHg at either Visit 2 or 3
3. Patients with secondary hypertension as a complication or patients suspected of having secondary hypertension(due to aortic coarctation, primary aldosteronism, coarctation of renal artery, renal hypertension
4. Patients suspected of having malignant hypertension