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| ID | Type | Description | Link |
|---|---|---|---|
| Impact N° 1457 | |||
| 2004-004962-33 | EudraCT Number |
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| Name | Class |
|---|---|
| Novartis Vaccines | INDUSTRY |
Kinetics of B cell response in infants Menjugate vaccination
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Meningococcal C conjugate vaccine | Biological |
| Measure | Description | Time Frame |
|---|---|---|
| To establish at which day meningococcal C specific B cells are detectable in the blood of healthy infants following first and third immunisation with MenC Conjugate Vaccine as determined by Men C specific B-cell ELISPot assay. |
| Measure | Description | Time Frame |
|---|---|---|
| To establish how long the B cells persist in the blood | ||
| To note the difference between plasma cell response following the first and third MenC vaccination. | ||
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| Name | Affiliation | Role |
|---|---|---|
| Novartis Vaccines - Information Services | Novartis Vaccines & Diagnostics | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital | Oxford | Oxon | OX3 7LJ | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19175802 | Background | Kelly DF, Snape MD, Perrett KP, Clutterbuck EA, Lewis S, Blanchard Rohner G, Jones M, Yu LM, Pollard AJ. Plasma and memory B-cell kinetics in infants following a primary schedule of CRM 197-conjugated serogroup C meningococcal polysaccharide vaccine. Immunology. 2009 May;127(1):134-43. doi: 10.1111/j.1365-2567.2008.02934.x. |
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| ID | Term |
|---|---|
| C410218 | serogroup C meningococcal conjugate vaccine |
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| To determine the immune response to Neisseria meningitidis serogroup C 26-34 days after the third immunisation |