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| ID | Type | Description | Link |
|---|---|---|---|
| CNMR grant, cardiff |
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Main hypothesis: microbiological diagnossis off severe community acquired pneumonia can be performed by non invasive or semi invasive microbiological tools, semi invasive tools including protected distal bronchial samplings by the mean of Fiber optic bronchoscopy (FOB). A microbiological diagnosis could improve antibiotic therapy efficacy and improve patient's outcome.
These Two strategies have never been prospectivally evauated.
ï‚·Type of study randomized multicentric controlled open study
Number of patients: 200 patients (100 patients in each group)admitted in ICU for SCAP
Main criteria: Changes in initial empirical antibiotic treatment according to microbiological results obtained in each group.
others
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| FOB protected distal microbiological samplings | Procedure |
Inclusion Criteria:
New radiological infiltrate SCAP clinical diagnosis admitted in ICU Admitted in hospital for less than 24 hours Aged 18 or older Signed informed consent
Exclusion Criteria:
Pregnancy Muribond patients Previuos hospitalisation within One month Neutropenia None HIV status
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| HERER BERTRAND, MD | Contact | +33141878801 | formation-aducation@cardif.asso.fr |
| Name | Affiliation | Role |
|---|---|---|
| RABBAT Antoine, MD | APHP | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hotel dieu | Recruiting | Paris | 75004 | France |
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