Use of Probiotic Bacteria in Prevention of Allergic Disea... | NCT00298337

Studies
Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008

NCT00298337

Sponsor

University of Helsinki

Status

Unknown status

Last Update Posted

Oct 18, 2006Estimated

Enrollment

Not provided

Phase

Phase 2Phase 3

Conditions

Atopic Dermatitis
Food Hypersensitivity
Allergic Rhinitis, Seasonal
Allergic Conjunctivitis
Asthma

Interventions

Mixture of probiotic bacteria and prebiotic oligosaccharide

Countries

Finland

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2006

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Active, not recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 1999

Primary Completion Date

Not provided

Completion Date

Dec 2007

First Submitted Date

Mar 1, 2006

First Submission Date that Met QC Criteria

Mar 1, 2006

First Posted Date

Mar 2, 2006Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Oct 17, 2006

Last Update Posted Date

Oct 18, 2006Estimated

Description Module

Brief Summary

The aim of the study is to find out if allergic diseases can be prevented buy giving probiotic bacteria to pregnant mothers and their newborn infants

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Phase 2Phase 3

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

Not provided

Name	Type	Description	Arm Group Labels	Other Names
Mixture of probiotic bacteria and prebiotic oligosaccharide	Drug

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

mother or father fo child with doctor diagnoses allergic disease

Exclusion Criteria:

prematurity, major malformations

Accepts Healthy Volunteers

Not provided

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

37 Weeks

Maximum Age

42 Weeks

Standard Ages

Child

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Erkki Savilahti, Professor	Helsinki University Central Hospital, Hospital for Children and Adults, PO Box 281, 00029 HUS, Finland	Study Chair

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Helsinki University Central Hospital, Skin and Allergy Hospital		Helsinki	PO Box 160	00029 HUS	Finland

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
38687061	Derived	Kallio S, Jian C, Korpela K, Kukkonen AK, Salonen A, Savilahti E, Kuitunen M, M de Vos W. Early-life gut microbiota associates with allergic rhinitis during 13-year follow-up in a Finnish probiotic intervention cohort. Microbiol Spectr. 2024 Jun 4;12(6):e0413523. doi: 10.1128/spectrum.04135-23. Epub 2024 Apr 30.
37438187	Derived

ID	Term
D003876	Dermatitis, Atopic
D005512	Food Hypersensitivity
D006255	Rhinitis, Allergic, Seasonal
D003233	Conjunctivitis, Allergic
D001249	Asthma

ID	Term
D012873	Skin Diseases, Genetic
D030342	Genetic Diseases, Inborn
D009358	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
D003872	Dermatitis