Study of Sentinel Lymph Node Assessment Following Previous Surgical Biopsy for Early Breast Cancer

Prospective Multicentric Study of Sentinel Lymph Node Assessment Following Previous Surgical Biopsy for Early Breast Cancer

The purpose of this study is to assess the detection rate and false negative rate of sentinel lymph node biopsy following previous surgical biopsy for early breast cancer diagnosis.

Inclusion Criteria:

• Age > 18 years
• Previous conservative surgical biopsy
• Secondary pathological diagnosis of infiltrative cancer
• No clinically involved axillary node (N0)
• No previous neoadjuvant treatment
• Performance status European Cancer Conference (ECCO) Grade ≤ 1
• Patient's written informed consent to participate in the study according to French law
• Surgeon must have performed its learning curve

Exclusion Criteria:

• Lack of infiltrative breast carcinoma (in situ) pT4d > N0
• Breast cancer relapse
• Pregnancy
• Known patent blue allergy
• Indication for radical or partial mastectomy
• Patient unable to understand the trial