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The purpose of this study is to develop effective exercise intervention to reduce dizziness and fall risk in older adults with non-specific dizziness. We hypothesize that the use of vestibular exercises can reduce dizziness and improve gaze and postural stability in older persons.
Community dwelling older individuals who present to a specialty dizziness clinic (Atlanta VAMC or Emory University) with a primary complaint of dizziness will be recruited to participate in this study. Before beginning the study, the presence of normal vestibular function will be measured directly using standard vestibular function tests. Individuals will be randomly assigned to the vestibular exercise group (VR) or to the control group (CON). Data will be collected prior to the initiation of physical therapy and at the completion of the 6-week intervention period.
The VR group will perform vestibular exercises plus balance and gait exercises. The CON group will perform saccadic eye movements without targets against a blank wall, as well as balance and gait exercises. The balance and gait exercises for each group will be based on identified impairments and functional limitations, as is the standard of care in physical therapy. All subjects within a group will follow the same exercise progression for the vestibular or eye movement exercises. Subjects will be seen in the clinic on a weekly basis to review and modify the exercises according to a standard protocol and to reinforce compliance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vestibular Rehabilitation | Experimental | vestibular exercises plus standard balance and gait exercises |
|
| Placebo | Placebo Comparator | placebo exercises plus standard balance and gait exercises |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vestibular rehabilitation | Behavioral | vestibular adaptation and substitution exercises |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dynamic Gait Index | Fall risk was determined using the Dynamic Gait Index (DGI). A maximum total score of 24 is possible and a total score of < 20 indicates risk for falling. | 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Dynamic Visual Acuity | Visual acuity during head movement (dynamic visual acuity, DVA) was measured using customized computerized software. DVA is measured in Logarithm of the Minimum Angle of Resolution (LogMAR). Participants identified letters while turning the head from side to side between 120 and 180 deg/s. DVA, the difference in acuity between head stationary and moving, is reported as the average of rightward and leftward scores; higher scores indicate worse visual acuity. |
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Inclusion Criteria:
Patients must be at least 60 years of age, seeking medical care due to dizziness and have normal vestibular function based on results of the clinical examination, rotary chair and/or caloric tests.
Exclusion Criteria:
Abnormal vestibular function based on results of clinical examination, rotary chair and/or caloric tests.
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| Name | Affiliation | Role |
|---|---|---|
| Courtney D. Hall, PhD PT | Mountain Home VA Medical Center James H. Quillen VA Medical Center, Mountain Home, TN | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Atlanta VA Medical and Rehab Center, Decatur | Decatur | Georgia | 30033 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20588090 | Result | Hall CD, Heusel-Gillig L, Tusa RJ, Herdman SJ. Efficacy of gaze stability exercises in older adults with dizziness. J Neurol Phys Ther. 2010 Jun;34(2):64-9. doi: 10.1097/NPT.0b013e3181dde6d8. |
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| ID | Title | Description |
|---|---|---|
| FG000 | Vestibular Rehabilitation | vestibular exercises plus standard balance and gait exercises Vestibular rehabilitation: vestibular adaptation and substitution exercises |
| FG001 | Placebo | placebo exercises plus standard balance and gait exercises Placebo Vestibular rehabilitation: placebo vestibular exercises |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | Vestibular Rehabilitation | vestibular exercises plus standard balance and gait exercises Vestibular rehabilitation: vestibular adaptation and substitution exercises |
| BG001 | Placebo |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Dynamic Gait Index | Fall risk was determined using the Dynamic Gait Index (DGI). A maximum total score of 24 is possible and a total score of < 20 indicates risk for falling. | Per-protocol analyses (i.e., only subjects who completed the intervention were included). | Posted | Mean | Standard Deviation | units on a scale | 6 weeks |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Vestibular Rehabilitation | vestibular exercises plus standard balance and gait exercises Vestibular rehabilitation: vestibular adaptation and substitution exercises |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Courtney D. Hall, PhD | James H. Quillen VAMC | 423-926-1171 | 7518 | courtney.hall@va.gov |
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| ID | Term |
|---|---|
| D004244 | Dizziness |
| ID | Term |
|---|---|
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Placebo | Behavioral | placebo vestibular exercises |
|
| 6 weeks |
placebo exercises plus standard balance and gait exercises
Placebo Vestibular rehabilitation: placebo vestibular exercises
| BG002 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Dynamic Gait Index | The Dynamic Gait Index (DGI) measures the ability to adapt gait to external demands and also is used to assess fall risk while walking. The eight items of the DGI include walking while changing speed and turning the head, walking over and around obstacles, and stair climbing. Scoring of the DGI is based on a 4-point scale from 0 to 3 with 0 indicating severe impairment and 3 indicating normal ability. A maximum total score of 24 is possible and scores of < 20 indicate risk for falling. | Mean | Standard Deviation | units on a scale |
|
| Dynamic Visual Acuity | Visual acuity during head movement (dynamic visual acuity, DVA) was measured using customized computerized software. Participants identified letters while turning the head from side to side between 120 and 180 deg/s. DVA, the difference in acuity between head stationary and moving, is reported as the average of rightward and leftward scores; higher scores indicate worse visual acuity (0.00 LogMAR = 20/20). | Mean | Standard Deviation | LogMAR |
|
|
|
|
| Secondary | Dynamic Visual Acuity | Visual acuity during head movement (dynamic visual acuity, DVA) was measured using customized computerized software. DVA is measured in Logarithm of the Minimum Angle of Resolution (LogMAR). Participants identified letters while turning the head from side to side between 120 and 180 deg/s. DVA, the difference in acuity between head stationary and moving, is reported as the average of rightward and leftward scores; higher scores indicate worse visual acuity. | Posted | Mean | Standard Deviation | LogMAR | 6 weeks |
|
|
|
|
| 0 |
| 20 |
| 0 |
| 20 |
| EG001 | Placebo | placebo exercises plus standard balance and gait exercises Placebo Vestibular rehabilitation: placebo vestibular exercises | 0 | 19 | 0 | 19 |
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main effect of time |
| 2-Sided |
| No |
| Superiority or Other |
| RM ANOVA | >.05 | Main effect of Group | 2-Sided | No | Superiority or Other |