This study aims to assess the analgesic effectiveness and safety of three different doses of a new formulation of Lamaline® versus Dafalgan® Codeine after 10 days administration in subjects with painful gonarthrosis

Inclusion Criteria:

• History of knee (unilateral or bilateral) osteoarthritis for at least 6 months
• Pain intensity assessed by Visual Analogue Scale ≥ 40 mm
• Partial functional disability assessed by Lequesne index ≥4 and < than 12

Exclusion Criteria:

• Patient unable to interrupt his/her NSAIDs to participate in the clinical study