Modulation of Visually Evoked Potentials by an Antidepressant

Modulation of Visually Evoked Potentials by an Antidepressant

12 normal healthy controls will be treated with 50 mg sertraline once daily for three weeks. Early amplitudes of visually evoked potentials will be examined at day 0, 10 and 21 and statistically compared. This study aims to examine a putative modulation of synaptic transmission and plasticity by an antidepressant and is part of a series of studies in healthy individuals and depressed patients.

Inclusion Criteria:

• healthy individuals 18-65 years

Exclusion Criteria:

• history of affective oder other psyhiatric disorder
• severe medical condition
• pregnancy or ineffective contraception
• active illicit drug use