Transdermal Application of Acetylcholine and Nitroglycerin Without Iontophoresis.
Transdermal Application of Acetylcholine and Nitroglycerin Without Iontophoresis.
This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).
Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.
Inclusion Criteria: diabetic. -
Exclusion Criteria: not on nitrates or mydriatic eye drops within 48 hours.
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