To verify of cetirizine dry syrup to ketotifen dry syrup in the change in the severity of pruritus of the treatment period.

Inclusion Criteria:

• Children diagnosed as atopic dermatitis
• Giving informed consent
• Children who have 2 grades or more pruritus score.
• Children who require the treatment with external steroid preparation other than face and head.
• Children with a pruritus severity of 2.
• Mild or severe on the fist day of the treatment period.

Exclusion criteria:

• have spastic disease such as epilepsy
• have a history of drug hypersensitivity
• are lactating or possibly pregnant female Children
• have a skin infection, or with zooparasite such as scabies and pediculosis
• cannot avoid the use of external steroid classified into strong, strongest or very strong
• have eczematous otitis externa with perforation in the eardrum
• have dermal ulcer, or profound heat burn or frostbite of the severity higher than the grade 2
• have asthma that requires the treatment with corticosteroid
• have pruritus only on face and head
• have inappropriate complication of dermal disorder that may influence on the evaluation of the study drug
• are undergoing specific desensitization therapy or immunomodulation therapy or phototherapy.