The Effects of Exenatide on Oral Contraceptive Pharmacokinetics in Healthy Females

The Effect of Exenatide on Single and Multiple Doses Oral Contraceptive Pharmacokinetics in Healthy Female Subjects

The purpose of this study is the examine the effect of taking exenatide on the blood levels (pharmacokinetics) of orally-administered contraceptives.

Inclusion Criteria:

• Pre-menopausal female of child-bearing potential.
• Body Mass Index (BMI) between 19 and 35 kg/m^2, inclusive.

Exclusion Criteria:

• On implanted contraceptives for 6 months, or injectable contraceptives for 12 months prior to the study.
• Evidence of diabetes mellitus.
• Participation in a study involving administration of an investigational compound within the past 3 months.