Safety and Efficacy of Seroquel in First Episode Schizophrenia

Safety and Efficacy of Seroquel in First Episode Schizophrenia

To compare the safety, tolerability and efficacy of Seroquel and risperidone in first episode schizophrenia

Inclusion Criteria:

• Age 18-35 years Meet ICD-10 criteria for schizophrenia No abnormaility on clinical examination No previous episode of psychosis No previous antipsychotics of any kind in last 3 months

Exclusion Criteria:

• Have received a course of antipsychotics drug treatment prior to entry which may introduce risk factors or interfere with study procedures Have received anticholinergics within 10 days of baseline aseessment Have received mood stabilizers or anti depressants within 2 weeks