A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of Caspofungin in the Treatment of Invasive Candidiasis in Adults

Comparison of the safety and effectiveness of standard drug dosing versus a daily dose 3 times higher than the standard dose in patients with invasive candidiasis (bloodstream and/or systemic yeast infections)

Inclusion Criteria:

• Clinical and Laboratory evidence of blood stream &/or systemic candida infections

Exclusion Criteria:

• Possible candida contamination
• Candida colonization (non invasive infection), urine, cardiac, bone or brain and prosthetic device infections
• Acute or moderately severe liver disease
• Abnormal liver function tests
• Abnormal blood clotting for patients on blood thinners