Redistribution of Fat and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

Redistribution and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

The purpose of this study is to learn whether HIV-infected patients have blood abnormalities which could lead to heart attack or stroke, and to find out what factors may contribute to these abnormalities.

This research is being done to learn whether HIV-infected patients have abnormalities in their blood vessels that could eventually lead to heart attack or stroke (atherosclerosis), in how fat is distributed in their body and in how their body handles fat and sugars. If there are abnormalities, this study will also try to find out what factors may contribute to those abnormalitites.

People who participated in FRAM 1 may join FRAM 2.

Inclusion Criteria:

• 18-65 years old
• previous FRAM 1 participant
• HIV positive

Exclusion Criteria:

• Artificial knee or hip replacement or Harrington rod
• Metal objects in the body.Pregnancy
• Breastfeeding or less than 3 months after breastfeeding
• Weight more than 300 pound
• On insulin, pancreatic enzymes, or thioridazine.