Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test

daily psoriasis plaque tests for two weeks and optical coherence tomography (OCT) and 20-MHz-ultrasound on day 0 and day 11, 10 days post end of treatment and 20 days post end of treatment

Inclusion Criteria:

• Patients older than 18 Years
• Negative urine pregnancy test
• Written informed consent
• Good compliance

Exclusion Criteria:

• Patients less than 18 years
• Pregnant patients
• Patients with renal insufficiency, liver diseases
• Patients who received systemic antipsoriatic treatment or UV treatment less than 4 weeks prior to study
• Patients who used topical antipsoriatics within two weeks prior to study
• Immunosuppressed Patients