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The purpose of this study is to investigate the ability of budesonide, given during episodes of troublesome lung symptoms to reduce further symptoms in infants and young children at risk of developing asthma
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pulmicort (budesonide) pMDI | Drug |
| Measure | Description | Time Frame |
|---|---|---|
| symptom free days | ||
| days with no use of bronchodilator | ||
| days with no use of bronchodilator and no symptoms | ||
| number of treated episodes | ||
| number of treatment with add-on medication |
| Measure | Description | Time Frame |
|---|---|---|
| asthma status | ||
| time to start of algorithm treatment | ||
| the total steroid dose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| AstraZeneca AB CNS Medical Science Director, MD | AstraZeneca | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Copenhagen | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16687712 | Result | Bisgaard H, Hermansen MN, Loland L, Halkjaer LB, Buchvald F. Intermittent inhaled corticosteroids in infants with episodic wheezing. N Engl J Med. 2006 May 11;354(19):1998-2005. doi: 10.1056/NEJMoa054692. |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| ID | Term |
|---|---|
| D019819 | Budesonide |
| ID | Term |
|---|---|
| D011282 | Pregnenediones |
| D011283 | Pregnenes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 |
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| First treatment episode: |
| number of symptom days |
| number of days with use of bronchodilator |
| number of patients who needed add-on medication |
| BMD |
| height |
| serious adverse events |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |