Studying the Analgesic Mechanism of the "Cough-trick" | NCT00233844

Studies
Studying the Analgesic Mechanism of the "Cough-trick"

NCT00233844

Sponsor

University Medicine Greifswald

Status

Completed

Last Update Posted

Jun 11, 2026Actual

Enrollment

21Actual

Phase

Not Applicable

Conditions

Pain
Acute Pain
Venipuncture

Interventions

Venipuncture with "cough-trick"

Countries

Not provided

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jun 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Feb 2004

Primary Completion Date

Mar 30, 2008Actual

Completion Date

Mar 30, 2008Actual

First Submitted Date

Oct 5, 2005

First Submission Date that Met QC Criteria

Oct 5, 2005

First Posted Date

Oct 6, 2005Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 8, 2026

Last Update Posted Date

Jun 11, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

The aim of the trial is to study the possible mechanism of the pain reducing effect of CT at peripheral venipuncture

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

21Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
cough-trick	Experimental	Venipuncture with cough-trick technique	Procedure: Venipuncture with "cough-trick"
without cough trick	No Intervention	Venipuncture without cough-trick technique

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Venipuncture with "cough-trick"	Procedure		cough-trick

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Pain intensity measured on 100 mm Visual Analogue Scale scale (VAS-100) where 0 = no pain and 100 = maximal pain		immediately during venipuncture

Secondary Outcomes

Measure	Description	Time Frame
Heart rate, beats per minute		5 min during venipuncture

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Male volunteers aged 20-40 years, height 165-190 cm.
Physical status I according to American Society of Anesthesiologists (ASA) classification.
Straight run of the vein on the dorsum of the non-dominant hand at least 4 cm long and 3 mm thick
No analgesics, anticoagulants and/or antiplatelet agents, sedatives or alcohol

Exclusion Criteria:

History of peripheral neuropathy
Abnormal skin conditions (infection, scars, psoriasis, eczema)
Unsuccessful venipuncture
Inflamed site of VP within 1 week after VP

Accepts Healthy Volunteers

Yes

Sex

Male

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

20 Years

Maximum Age

35 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Taras I. Usichenko, Assistant Professor	Anesthesiology and Intensive Care Medicine Department, Ernst Moritz Arndt University of Greifswald, Germany	Principal Investigator

Locations

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D010146	Pain
D059787	Acute Pain

Ancestor Terms

ID	Term
D009461	Neurologic Manifestations
D012816	Signs and Symptoms
D013568	Pathological Conditions, Signs and Symptoms

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D018962	Phlebotomy

Ancestor Terms

ID	Term
D001800	Blood Specimen Collection
D013048	Specimen Handling
D019411	Clinical Laboratory Techniques
D019937	Diagnostic Techniques and Procedures

Browse Leaves

Not provided

Browse Branches

Not provided