Study to Determine Racial and Gender Differences in Platelet Aggregation

Phase 1 Study to Determine Racial and Gender Differences in Platelet Aggregation

The purpose of this study is to see if there is a racial and/or gender difference in platelet aggregation.

Genetic variability of various components of the coagulation system has been reported. Data on racial and gender differences in platelet aggregation are lacking.

We hypothesize that there are significant racial and gender differences on aggregatory response of platelets to commonly used agonists to evaluate platelet function such as adenosine diphosphate (ADP), epinephrine, collagen and arachidonic acid.

Inclusion Criteria:

• Race of Caucasian, African American, or Hispanic

Exclusion Criteria:

• Chronic medical conditions
• Tobacco use
• Regular non-steroidal anti-inflammatory use, aspirin use, or use of one of the other anti-platelet drugs.