Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery

The aim of this trial was to characterise the intra and post operative metabolic, endocrine and inflammatory response to laparoscopic fundoplication in children. We are testing the hypothesis that laparoscopic fundoplication is associated with a lack of hypermetabolism and catabolism and blunting of the endocrine/inflammatory stress response

Inclusion Criteria:

• infants and children with gastro-oesophageal reflux

Exclusion Criteria:

• septic shock, multi-organ dysfunction syndrome, cardiac, renal or congenital metabolic abnormalities