Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects

A Randomized, Open-Label, Comparative, Two-Treatment, Crossover Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects on Days 1 and 5 of Intravenous Treatment

This study is intended to evaluate whether intravenous (iv) esomeprazole (Nexium® ) offers better intragastric acid suppression than iv lansoprazole (Prevacid ®

Inclusion Criteria:

• Participants must be 18-70 years of age
• Participants can be male or female
• Women that are able to have children must have a negative pregnancy test.

Exclusion Criteria:

• Involvement in or planning of this study
• Participation in another clinical study within 28 days of this one
• For women, pregnancy or attempting to become pregnant.