Study of Medication and Placebo Response in Major Depression

The primary purpose of the research study is to use recordings of brain electrical activity (through electroencephalogram, or EEG) and symptom measurements to determine whether patients are likely to show a response to medication or placebo treatment during a treatment trial for depression.

Inclusion Criteria:

• Clinical Diagnosis of Unipolar Major Depression

Exclusion Criteria:

• Substance Abuse, Psychotic Disorder, History of Severe Head Trauma