Treatment of Mild and Subthreshold Depressive Disorders

Behandlung Von Leichten Und Unterschwelligen Depressionen. Eine Randomisierte, Kontrollierte Studie Zum Wirksamkeitsnachweis Eines Serotonin-Wiederaufnahme-Hemmers (SSRI), Einer Kognitiven Verhaltenstherapie Und Einer Freien Therapiewahl ("Treatment of Mild and Subthreshold Depressive Disorders". A Randomized, Controlled Trial on the Efficacy of a Serotonin-Reuptake-Inhibitor (SSRI), a Cognitive-Behavioral Therapy and of Free Choice Between SSRI and CBT")

The purpose of this study is to determine the efficacy of a SSRI, cognitive-bahavioral-therapy and a free choice between SSRI and CBT in a sample of primary care patients suffering from mild to moderate depression.

Hypotheses:

• SSRI is superior to placebo
• CBT is superior to a non-specific supporting group therapy

Inclusion Criteria:(e.g.)

• subthreshold and mild depressive disorders including dysthymia (HAMD: 8-22)
• informed consent
• 18 years

Exclusion Criteria:(e.g.)

• severe mood disorders
• bipolar disorder
• recurrent brief depression
• suicidality
• alcohol or drug dependency
• obsessive-compulsive disorder
• schizoaffective disorder / schizophrenia
• pregnancy