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| ID | Type | Description | Link |
|---|---|---|---|
| 2005-0122 | Other Identifier | Institutional Review Board | |
| A533300 | Other Identifier | UW Madison | |
| SMPH/HUMAN ONCOLOGY | Other Identifier | UW Madison |
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The purpose of this study is to compare the baseline incidence of variant alleles in the ATM and/or other DNA repair genes present in the Native American population versus the non-Native American population. It is thought that a higher baseline incidence of the variant alleles in the ATM gene may correlate to higher rates and higher grades of radiation toxicities noted in the Native American population.
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| Measure | Description | Time Frame |
|---|---|---|
| to determine baseline incidence of variant alleles in ATM | to determine the baseline incidence of variant alleles in ATM resent in the population of Native americans with cancer who are undergoing radiation therapy to a similar group of non-native americans who have undergone or are undergoing raditohterapy | one blood draw |
| Measure | Description | Time Frame |
|---|---|---|
| to compare the baseline incidence of variant alleles in ATM | to compare the baseline incidence of variant alleles in ATM resent in the population of Native americans with cancer who are undergoing radiation therapy to a similar group of non-native americans who have undergone or are undergoing raditohterapy | one blood draw |
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Inclusion Criteria:
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Patients who have been enrolled on RO02803.
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| Name | Affiliation | Role |
|---|---|---|
| Mark Ritter, MD, PhD | University of Wisconsin, Madison | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | United States |
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| Label | URL |
|---|---|
| University of Wisconsin Carbone Cancer Center | View source |
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direct sequence analysis of all exons and intron-exon junctions of the ATM gene. DNA will be isolated from lympocytes using the PAX blood DNA system.