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| Name | Class |
|---|---|
| Alcon Research | INDUSTRY |
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Retinal Vein Occlusion is a blockage of the blood vessels that drain out of the retina. Complications of retinal vein occlusion which threaten vision include neovascularization(growth of new blood vessels)and macular edema ( accumulation of fluid "leaking" from abnormal blood vessels). Currently, the treatment of retinal vein occlusion is laser photocoagulation. This treatment has found to have limited use in this type of condition.Anecortave Acetate is being considered as an attempt to control the growth of the abnormal blood vessels.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| anecortave acetate | Experimental | anecortave acetate 15 mg. juxtascleral injection every 6 months for 24 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anecortave Acetate | Drug | ancortave acetate 15 mg. juxtascleral injection every 6 months for 24 months. |
|
| Measure | Description | Time Frame |
|---|---|---|
| to investigate the use of anecortave acetate for treatment of retinal vein occlusion | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| mean change of VA (ETDRS) from baseline to 24 months | 24 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lawrence A. Yannuzzi, MD | Manhattan Eye, Ear & Throat Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Manhattan Eye, Ear & Throat Hospital | New York | New York | 10021 | United States |
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| ID | Term |
|---|---|
| D012170 | Retinal Vein Occlusion |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D020246 | Venous Thrombosis |
| D013927 | Thrombosis |
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| ID | Term |
|---|---|
| C418047 | anecortave acetate |
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| D016769 |
| Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |