Surveillance For New Lung Primaries

Fluorescence Bronchoscopic Surveillance For New Lung Primaries After Curative Therapy for Squamous Cell Carcinoma of the Aerodigestive Tract"

The primary goal of this study is to determine the prevalence of tracheobronchial carcinomas in patients with a history of squamous cell cancer of the aerodigestive tract who have been treated with a curative intent and remain disease free. Detection of pre-invasive and invasive lesions (moderate to severe dysplasia, CIS) with fluorescence bronchoscopic surveillance may help to define the natural history of these lesions and allow earlier intervention should they progress to invasive lesions.

Inclusion Criteria:

• History squamous cell NSCLC who have undergone complete resection or definitive chemotherapy

Exclusion Criteria:

• History of an aerodigestive tract carcinoma of non-squamous histology
• Patients who have Stage IIIA, IIIB or IV squamous cell lung cancer that have undergone resection or chemotherapy within three years
• Patients who have Stage I or II squamous cell lung cancer that have undergone resection or chemotherapy within one year
• Patients who have received external beam radiation therapy for treatment of a squamous cell cancer of the lung