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| Name | Class |
|---|---|
| Free State Department of Health | UNKNOWN |
| Medical Research Council, South Africa | OTHER |
| University of Toronto | OTHER |
| Institute for Clinical Evaluative Sciences |
A scale-up of public sector antiretroviral treatment (ART) programmes may divert scarce resources from other priority primary care programmes like tuberculosis and childhood immunization.
The purpose of this study is to compare the performance of tuberculosis (TB) and childhood immunization programmes in primary care facilities participating in the South African national antiretroviral treatment programme with those which have yet to be included in the ART programme.
Large-scale public sector antiretroviral treatment programmes, like those planned for sub-Saharan Africa, will compete for scarce resources, in particular scarce human resources, with other priority primary care programmes like tuberculosis and childhood immunization.
This could lead to impaired performance in other priority programmes like childhood immunization while health workers are distracted by the demands of establishing and maintaining ART programmes. On the other hand, ART provisions may have positive spin-offs for related programmes like improved case detection of tuberculosis among HIV-positive patients seeking ART. The impact of the ART programme on primary healthcare more generally must be weighed against the benefits of providing antiretroviral treatment to those with AIDS.
Comparison: Primary care clinics in the Free State province, South Africa. 15 clinics participating in the first phases of the national ART programme will be compared with 24 clinics which have yet to be included in the national treatment programme. The unit of analysis will be the clinic although the outcome data will be collected from individual patients.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Public sector antiretroviral treatment programmes | Behavioral |
| Measure | Description | Time Frame |
|---|---|---|
| TB case detection | ||
| TB treatment completion | ||
| Measles immunization completed by 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| TB cure rate | ||
| TB mortality rate | ||
| TB treatment failure rate |
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Inclusion Criteria:
Clinics:
Patients:
Exclusion Criteria:
Clinics:
Patients:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| L R Fairall, MBChB | Contact | +27 21 4066919 | 6919 | lfairall@uctgsh1.uct.ac.za |
| G M Rembe, BSc(Hons) | Contact | +27 21 4066928 | 6928 | grembe@uctgsh1.uct.ac.za |
| Name | Affiliation | Role |
|---|---|---|
| L R Fairall, MBChB | University of Cape Town Lung Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Cape Town Lung Institute | Recruiting | Cape Town | Western Cape | 7937 | South Africa |
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| ID | Term |
|---|---|
| D014376 | Tuberculosis |
| ID | Term |
|---|---|
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
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| OTHER |
| London School of Hygiene and Tropical Medicine | OTHER |
| University of the Western Cape | OTHER |
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| TB treatment interruption rate |
| Proportion of TB cases that smear positive |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |