Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome

Efficacy and Safety of Ecabet Ophthalmic Solution (2.83% and 3.70%) for Treatment of Dry Eye Syndrome

The purpose of this study is to determine whether ecabet ophthalmic solution is an effective treatment for dry eye syndrome

Inclusion Criteria:

• Agree to avoid systemic & topical ophthalmic meds & disallowed meds
• Have a best corrected visual acuity (BCVA) of 20/40 with pinhole or better in each eye
• Diagnosis of moderate dry eye syndrome

Exclusion Criteria:

• Uncontrolled ocular or systemic disease that could interfere with study
• Diagnosis of Sjogren's syndrome, lacrimal obstruction, reflex, lid-related or contact lens-related dry eye syndrome(DES); significant anterior blepharitis or meibomianitis
• Contraindications or hypersensitivity to use of study meds or components
• Wear contact lenses
• Secondary dry eye to surgery
• Eye surgery (including laser) within 6 months
• Use of systemic or topical ophthalmic meds within 14 days
• Punctal plugs in one or both eyes in place for <45 days
• Permanent occlusion of the lacrimal puncta