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The purpuse of this study is to examine the acute phase respons when different doses of E. Coli Endotoxin is injected in healty volunters.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| E. Coli endotoxin | Drug |
Inclusion Criteria: Healty volunteers -
Exclusion Criteria:
Infection 14 days prior to the trial Regular medication Present and /or former heart disease -
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| Name | Affiliation | Role |
|---|---|---|
| Bente K Pedersen, MD, DMSc | Department of Infectious Diseases 7641, University Hospital of Copenhagen, H:S Rigshospitalet | Study Chair |
| Dorthe H Olsen, MD | Department of Intensive Care, Herlev University Hospital | Principal Investigator |
| Dorthe H Olsen, DM | Department of Intensive Care, Herlev University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Intensive Care | Copenhagen | Copenhagen County | 2730 | Denmark |
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| ID | Term |
|---|---|
| D019446 | Endotoxemia |
| D018805 | Sepsis |
| ID | Term |
|---|---|
| D016470 | Bacteremia |
| D007239 | Infections |
| D014115 | Toxemia |
| D018746 | Systemic Inflammatory Response Syndrome |
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| ID | Term |
|---|---|
| C044101 | endotoxin, Escherichia coli |
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| D007249 |
| Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |