Study Evaluating Sirolimus in Kidney Transplant Recipients

A Randomized Open-Label Study Comparing the Efficacy and Safety of Sirolimus Combined With Daclizumab, Mycophenolate and Corticosteroids vs Cyclosporine, Mycophenolate and Corticosteroids in Renal Allograft Recipients Receiving Kidneys From Older Donors

The purpose of this study is to compare the kidney function in patients who have received a transplanted kidney and were treated with the combination of sirolimus, daclizumab, mycophenolate and corticosteroids versus transplanted patients treated with cyclosporine, mycophenolate and corticosteroids.

Inclusion Criteria:

• Kidney transplantation
• Donor must be at least 60 years old.

Exclusion Criteria:

• Current systemic infection
• Unstable angina or treatment for serious arrhythmia.
• Cancer within the previous 5 years.