The Serotonergic Transmitter System in Dementia and Affec... | NCT00192998

Studies
The Serotonergic Transmitter System in Dementia and Affective Disorders

NCT00192998

Sponsor

Rigshospitalet, Denmark

Status

Unknown status

Last Update Posted

Sep 27, 2007Estimated

Enrollment

100Estimated

Phase

Not provided

Conditions

Mood Disorders
Alzheimer Disease

Interventions

Not provided

Countries

Denmark

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Sep 2005

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 2003

Primary Completion Date

Not provided

Completion Date

Not provided

First Submitted Date

Sep 13, 2005

First Submission Date that Met QC Criteria

Sep 13, 2005

First Posted Date

Sep 19, 2005Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Sep 26, 2007

Last Update Posted Date

Sep 27, 2007Estimated

Description Module

Brief Summary

The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography [PET]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

100Estimated

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Moderate to severe Alzheimer's disease
Individuals genetically predisposed to affective disorder
Healthy gender and age matched controls

Exclusion Criteria:

Contraindications to magnetic resonance imaging (MRI)
Use of psychoactive drugs
Past or present affective disorder
Other systemic diseases that may affect brain function

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Vibe G. Frokjaer, MD	Contact	+45 3545 6714		vibe@nru.dk
Steen G. Hasselbalch, MD	Contact			sgh@nru.dk

Overall Officials

Name	Affiliation	Role
Vibe G. Frokjaer, MD	Neurobiological Research Unit, Copenhagen University Hospital, Denmark	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Neurobiological Research Unit	Recruiting	Copenhagen		2100	Denmark

Label	URL
homepage for the neurobiological research unit, Copenhagen, Denmark	View source

Condition Browse Module

MeSH Terms

ID	Term
D019964	Mood Disorders
D000544	Alzheimer Disease

Ancestor Terms

ID	Term
D001523	Mental Disorders
D003704	Dementia
D001927	Brain Diseases
D002493	Central Nervous System Diseases

Browse Leaves

Not provided

Browse Branches

Not provided