Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder

Insulin Sensitivity in Patients With Schizophrenia or Schizoaffective Disorder Treated With Olanzapine and Risperidone

This study will assess whether olanzapine and/or risperidone affect the way the human body uses sugar in the blood.

Inclusion Criteria:

• 18-65 years old
• Diagnosed with Schizophrenia or Schizoaffective disorder
• Ability to visit the doctor's office for scheduled visits

Exclusion Criteria:

• Women who are pregnant or breastfeeding
• Have a body mass index (BMI) greater than 40
• Have diabetes, heart disease or any other unstable illness
• Have known positive human immunodeficiency virus (HIV)
• Are currently taking olanzapine, risperidone, clozapine, glucocorticoids, injectable antipsychotics