Efficacy and Safety of Duloxetine

Efficacy and Safety of Duloxetine Compared With Placebo in Subjects Electing Surgery for Severe Pure Genuine Stress Incontinence

The purpose of this study is to monitor the long term safety and efficacy of duloxetine in the treatment of severe pure genuine stress incontinence.

Inclusion Criteria:

• Female out patients.
• Have a diagnosis of pure genuine stress incontinence on urodynamic study performed within 6 months prior to study entry.

Exclusion Criteria:

• Use of monoamine oxidase inhibitors within 14 days prior to study entry or at any time during the study.
• Suffer from severe constipation.