Expectant Versus Immediate Medical Management for the Evacuation of the no Evolutionary Pregnancies Before 13 GW

Comparison Expectant With Immediate Medical Management for the Evacuation of the no Evolutionary Pregnancies Before 13 GW

Compared the interest of one week expectancy vs immediate medical treatment in the taking care of the evacuation of the no evolutionary pregnancies before 13 GW.

Randomized control trial comparing one week expectancy vs immediate medical treatment (mifepristone 200mg and misoprostol 400ug) in the taking care of the evacuation of the no evolutionary pregnancies before 13 GW.

Inclusion Criteria:

• Agreed women aged over 18 yrs old

Non evolutive pregnancy before 13GW :

• Non evolutive pregnancy with no fetal cardiac activity
• Non evolutive pregnancy with embryonic structures
• Trophoblastic material in uterine cavity P bhCG < 10UI/L

Exclusion criteria:

• Age < 18 years
• pregnancy evolutionary
• not evolutionary pregnancy after 13 weeks of amenorrhoea characterized by the presence of an scan image intra-uterine ANECHOGENE furthermore of 50mm of diameter
• amenorrhoea of more than 13 weeks
• pregnancy twin
• pregnancy molar
• pregnancy extra-uterine
• Extra-uterine pregnancy
• one or many contraindications in the mifepristone:
• Allergy known about the MIFEPRISTONE
• Incapacity suprarenal
• corticosteroid therapy in the long price
• confusions of the haemostasis (thrombopenia < in 100000 / mm3)
• anaemia (rate Hg < in 9 g / dl)
• contraindication in the misoprostol
• allergy known about PROSTAGLANDINES
• BEANCE cervical