Cardiopulmonary Bypass (CPB) Pumps and Blood Activation

Blood Activation During Cardiopulmonary Bypass Using Roller or Centrifugal Pumps

Blood activation induced by cardiopulmonary bypass may compromise the postoperative outcome. The goal of this study is to compare blood activation induced by cardiopulmonary bypass performed with centrifugal pump or roller pump in patients undergoing coronary artery surgery.

Inclusion Criteria:

• Men undergoing coronary artery bypass grafting using cardiopulmonary bypass
• Aspirin therapy

Exclusion Criteria:

• Redo surgery
• Acute coronary syndrome requiring urgent surgery
• Oral anticoagulant therapy
• Organ dysfunction or chronic inflammatory disease
• Surgery other than coronary artery bypass grafting