Transcranial Magnetic Treatment (TMS) in Unipolar Depression

Repetitive Transcranial Magnetic Stimulation (rTMS) in Unipolar Depression

Repetitive Transcranial Magnetic Stimulation (rTMS) can improve mood and decrease sadness in patients with depression.

In this study, the investigators seek to increase their understanding about how rTMS improves depression, and to determine which form of rTMS is most effective for depression, when used in combination with antidepressant medication.

Patients will be assigned for 4 treatment arms, receiving either left high frequency plus right low frequency, or left high frequency plus right sham, or left sham, plus right low frequency, or left sham plus right sham treatment. All subjects will receive treatments for 10 days and will be followed for another 4 weeks.

Inclusion Criteria:

• Major Depression
• No physical health problems

Exclusion Criteria:

• History of Epilepsy
• Metal in the head/neck or skull
• Pacemaker
• Pregnancy