Dose-Response of Exercise on Long-Term Weight Loss
Dose-Response of Exercise on Long-Term Weight Loss
ClinicalTrials.gov ID
NCT00177762
Lead Sponsor
University of PittsburghOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Phase 1Phase 2
Enrollment
200
Last Update Posted
Sep 15, 2005Estimated
Start Date
Sep 1999
Completion Date
Dec 2002
Official Title
Dose-Response of Exercise on Long-Term Weight Loss
Brief Summary
The purpose is to examine varying durations and intensities of exercise on long-term weight loss.
Obesity
Weight Loss
behavior weight loss
Ages Eligible for Study
Adult (18-64)
Sexes Eligible for Study
Female
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Female
21-45 years of age
BMI = 27-40 kg/m2
Ability to provide informed consent.
Ability to provide consent from their personal physician to participate in this study.
Exclusion Criteria:
Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.)
Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism.
Currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 24 months. (Pregnancy will be based on self-report and will be included on the detailed medical history that is completed by subjects.)
Non-medicated resting systolic blood pressure >160 mmHg or non-medicated resting diastolic blood pressure >100 mmHg, or taking medication that would affect blood pressure.
Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade).
Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated.
History of myocardial infarction or valvular disease.
History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).