Subthalamic Nucleus (STN) Stimulation and Obsessive-Compulsive Disorder (OCD)

Study of the Effects of High Frequency Stimulation of the Subthalamic Stimulation in the Treatment of Severe Obsessive-compulsive Disorders

Obsessive-compulsive disorder is a disabling and frequent disorder. In some patients, the medical treatment is ineffective. The pathophysiology of this disease is still unknown. Some data suggest that basal ganglia dysfunction could participate in the occurrence of OCD. The aim of this study is to evaluate the efficacy of subthalamic nucleus high-frequency stimulation in patients with severe OCD.

Inclusion Criteria:

• Severe obsessive-compulsive disorder

Exclusion Criteria:

• Contraindication to magnetic resonance imaging (MRI)
• Severe cognitive or behavioral disorders