CompletedInterventionalPhase 4Updated Jan 28, 2016
The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia. | NCT00165711 | Trialant
CompletedInterventionalPhase 4Updated Feb 19, 2019
The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia.
ClinicalTrials.gov ID
NCT00165711
Lead Sponsor
Eisai Co., Ltd.INDUSTRY
Overall Status
Completed
Study Type
Interventional
Phase
Phase 4
Last Update Posted
Feb 19, 2019Actual
Start Date
Mar 2003
Brief Summary
Patients who fit the inclusion criteria are admitted into the study. They are given 3 IV injection of MBL in the first week and one tablet three times a day for 16 weeks.
Dementia With Vitamin B12 Deficiency
Mecobalamin
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No data available
Eligibility Criteria
Inclusion:
Patients with Dementia
Serum B12 < 200 pmol/l
Serum Homocysteine level > 11.0 micro mol/L
Exclusion:
Significant communication problems
deafness, dysarthria, dysphasia etc.
unstable DM or hypertension
alcohol abuse
co-existing diseases which may affect cognition e.g. cognitive cardiac failure, respiratory failure