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| Name | Class |
|---|---|
| Brigham and Women's Hospital | OTHER |
| Beth Israel Deaconess Medical Center | OTHER |
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The purpose of this study is to determine if the use of breast MRI in detecting breast malignancies in survivors of Hodgkin's disease is more successful than the traditional mammogram.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| breast MRI | Procedure | Repeated once a year for three years | ||
| Mammogram | Procedure | Repeated once a year for three years |
| Measure | Description | Time Frame |
|---|---|---|
| To compare the sensitivity, specificity, positive and negative predictive value of mammography and breast MRI for breast cancer detection in women treated for Hodgkin's disease. | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| To describe the MRI appearance and enhancing characteristics of breast cancer after Hodgkin's disease | 5 years | |
| to correlate the breast MRI findings and pathological findings | 5 years | |
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Inclusion Criteria:
Exclusion Criteria:
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Survivors of Hodgkin's disease that have been previously received radiation therapy to the chest area
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| Name | Affiliation | Role |
|---|---|---|
| Andrea K. Ng, MD | Dana-Farber Cancer Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | United States | ||
| Dana-Farber Cancer Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23610104 | Derived | Ng AK, Garber JE, Diller LR, Birdwell RL, Feng Y, Neuberg DS, Silver B, Fisher DC, Marcus KJ, Mauch PM. Prospective study of the efficacy of breast magnetic resonance imaging and mammographic screening in survivors of Hodgkin lymphoma. J Clin Oncol. 2013 Jun 20;31(18):2282-8. doi: 10.1200/JCO.2012.46.5732. Epub 2013 Apr 22. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D006689 | Hodgkin Disease |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| to determine the incidence of interval breast cancer in the screened population. |
| 5 years |
| Boston |
| Massachusetts |
| 02115 |
| United States |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States |
| D017437 |
| Skin and Connective Tissue Diseases |
| D008223 | Lymphoma |
| D009370 | Neoplasms by Histologic Type |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |